Neuropharmacology & Neurotherapeutics
Levodopa is the gold standard for the treatment of Parkinson disease. It is a precursor for dopamine, and its anti–Parkinson disease effects are mediated by the synthesis of dopamine, which subsequently interacts with dopamine receptors. To overcome the short half-life of levodopa, it is usually combined with the decarboxylase inhibitor, carbidopa. Several movement disorders can occur as adverse effects of levodopa therapy.
Apr. 03, 2021