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Damage to the tongue and lip from self-mutilation behavior in a patient with Lesch-Nyhan disease

Clinical presentation of the patient with Lesch-Nyhan disease at eight months of age. An ulcer involves the tip of the tongue with well-defined regular borders and a yellowish central membrane. The lower lip exhibits deformity. Erythematous patches are evident in the perioral skin. (Source: Eita AA. Congenital anomalies-associated Riga-Fede disease as an early manifestation of Lesch-Nyhan syndrome: rare entities in the same pediatric patient-a case report. BMC Oral Health 2022;22(1):26. Creative Commons Attribution License.

Associated Disorders

  • Choreoathetosis
  • Dystonia
  • Gout
  • Hyperuricemia
  • Intellectual disability
  • Renal stones