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Stones discharged after the spontaneous rupture of a left ankle tophus in a patient with Lesch-Nyhan disease

In a 15-year-old boy with Lesch-Nyhan disease, a tophus of the left ankle burst and discharged stones. (Source: Ambarsari CG, Cahyadi D, Sari L, et al. Late diagnosis of Lesch-Nyhan disease complicated with end-stage renal disease and tophi burst: a case report. Ren Fail 2020;42(1):113-21. Creative Commons Attribution License.

Associated Disorders

  • Choreoathetosis
  • Dystonia
  • Gout
  • Hyperuricemia
  • Intellectual disability
  • Renal stones