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SPECT-CT and Tc-99m sestamibi scintigraphy of parathyroid glands

Transaxial (A), sagittal (B), and coronal (C) perspectives, showing (arrows) focal area of increased radiotracer concentration in the right side of the neck at the level of C5-C7 vertebra suggestive of parathyroid adenoma or carcinoma. Delayed static image of Tc-99m sestamibi parathyroid scintigraphy (D), showing (arrow) persistent focal activity in the abovementioned area. Legend: SPECT-CT: single-photon emission computed tomography-computed tomography. (Source: Huq MR, Hossain A, Hannan MA, Anwar MB, Khan AM. Proximal myopathy with hypercalcemic crisis and papillary thyroid carcinoma in a 38-year-old female. Cureus 2021;13[12]:e20700. Creative Commons Attribution [CC-BY 4.0] license,

Associated Disorders

  • Calciphylaxis
  • Chronic renal failure
  • DiGeorge Syndrome
  • Hemochromatosis
  • Osteitis fibrosa cystica
  • Osteomalacia
  • Parathyroid adenocarcinoma
  • Parathyroid adenoma
  • Wilson disease