Stroke & Vascular Disorders
Hypertensive intracerebral hemorrhage
Apr. 21, 2023
Nearly 3,000 illustrations, including video clips of neurologic disorders.
Every article is reviewed by our esteemed Editorial Board for accuracy and currency.
Full spectrum of neurology in 1,200 comprehensive articles.
Listen to MedLink on the go with Audio versions of each article.
The biosynthesis of steroid hormones derives from cholesterol, a molecule with 4 linked rings and 27 carbons. Cholesterol is first converted to a series of progestogens with 21 carbons. Progestogens can be converted by hydroxylation (at carbon 21) to mineralocorticoids or glucocorticoids (both with 21 carbons) or by an elimination reaction to androgens (with 19 carbons). Androgens can in turn be converted to estrogens (with 18 carbons) by the action of an aromatase enzyme that converts ring A to a monocyclic aromatic 6-carbon ring. (Source: Diagram of the pathways of human steroidogenesis. WikiJournal of Medicine 2014. Creative Commons Attribution-Share Alike 3.0 Unported license.)