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Intercurrent crises in patient with mevalonic aciduria

Patient with mevalonic aciduria 6 years of age during intercurrent crises with high fever, diarrhea, vomiting, hepatosplenomegaly, and rashes. In this girl, these conditions occurred fortnightly. (Reproduced with permission from: Haas D, Kelley RI, Hoffmann GF. Inherited disorders of cholesterol biosynthesis. Neuropediatrics 2001;32(3):113-22.)

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Associated Disorders

  • Hyperimmunoglobulinemia D and periodic fever syndrome
  • Periodic fever, Dutch type