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This T2-weighted image, taken when the patient was 5 years, 8 months old, shows that her condition had deteriorated.
Neuro-Ophthalmology & Neuro-Otology
Oct. 21, 2020
Core myopathies represent the most common form of congenital myopathies, involving early-onset neuromuscular disease that often presents with stable or slowly progressive truncal and proximal weakness. There is a wide clinical spectrum, with severity ranging from mild to severe. Central core disease and multiminicore disease are the most common congenital myopathy forms.
Jun. 29, 2020
Anxiety and depression are strongly associated with dizziness. Psychophysiological dizziness is generally characterized as a vague giddiness or dissociated sensation due to impaired central integration of sensory and motor signals in patients with acute and chronic anxiety. The dizzy sensation is typically persistent, protracted or continuous, with periodic exacerbations, often punctuated by episodes of hyperventilation-induced presyncope. Specific provocative factors may be identified.
May. 16, 2020
Muscle and nerve biopsies may provide valuable information for clinicians evaluating patients with neuromuscular conditions. Both open and needle muscle biopsy techniques have been used. Interpretation of muscle and nerve biopsies requires a very careful correlation of the pathological findings with the clinical information and other laboratory investigations. Histological, enzyme histochemical, electron microscopical, and immunohistochemical techniques are used in muscle and nerve pathology.
Aug. 08, 2021
Behavioral & Cognitive Disorders
Alzheimer disease (AD) is a neurodegenerative disease that causes dementia, most often starting with memory loss. Its hallmark microscopic features are neurofibrillary tangles and amyloid plaques. Other symptoms may include anomia, visuospatial deficits, executive dysfunction, apathy, depression, and agitation.
Feb. 19, 2020
Aug. 06, 2020
Creutzfeldt-Jakob disease (CJD) is a member of the group of diseases known as prion diseases or the subacute spongiform encephalopathies. CJD is a subacute fatal disease with a clinical triad of dementia, myoclonus, and EEG abnormalities that is usually associated with other neurologic signs, along with neuropathological evidence of neuronal loss, spongiform changes, and astrocytosis.
Apr. 23, 2021