Neuro-Ophthalmology & Neuro-Otology
Leber hereditary optic neuropathy
Mar. 13, 2022
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(A) Multifocal visual evoked potential stimulus contains 60 sectors of black and white checks (one sector shown in red). (B) Multifocal visual evoked potential responses from the right eye (blue) and the left eye (red) of a normal subject are very similar. (C) The multifocal visual evoked potential responses from the right eye with a history of optic neuritis are delayed in some sectors compared to those from the left eye (red). (D) An interocular latency probability plot marks the locations with significantly delayed latencies in the right eye with an optic neuritis history (dark blue for p < 0.01, light blue for p < 0.05) compared to the left eye. Black symbols denote no significant differences compared to a normative database; small gray symbols denote responses too small for comparisons. (Contributed by Dr. Han Cheng.)