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Perifascicular atrophy and inflammatory infiltrates and scattered necrotic fibers

Panel A: Perifascicular atrophy and inflammatory infiltrates in a patient diagnosed with dermatomyositis (hematoxylin and eosin-stained muscle biopsy specimen). Panel B: Scattered necrotic fibers invaded by macrophages in a patient with necrotizing autoimmune myositis (trichrome-stained cross-section). (Contributed by Josep Maria Grau-Junyent, Muscle Research Unit, Hospital Clinic, Universitat de Barcelona, Barcelona, Spain.)