General Child Neurology
Infant botulism is a serious bacterial infection that results from ingestion of Clostridium botulinum spores that colonize the intestinal tract, releasing botulinum toxin and resulting in progressive neuromuscular weakness. It presents with a progression of symptoms: constipation, cranial nerve palsies, flaccid descending paralysis, and possible respiratory failure. Treatment includes urgent administration of botulism immune globulin (BabyBIG®) as well as supportive care.
May. 31, 2021