Sign Up for a Free Account

This is an image preview.
Start a Free Account
to view the full image.

Sign Up for a Free Account For information on discounts, see Plans & Pricing

  • Nearly 3,000 illustrations, including video clips of neurologic disorders.

  • Every article is reviewed by our esteemed Editorial Board for accuracy and currency.

  • Full spectrum of neurology in 1,200 comprehensive articles.

  • Listen to MedLink on the go with Audio versions of each article.

Schematic location and functioning of cellular folate transporters FRα and PCFT in the transcytosis of folate in the renal tubular epithelium

Schematic location and functioning of cellular folate transporters FRα and PCFT in the transcytosis of folate in the renal tubular epithelium}{label:Renal reabsorption of folates from glomerular filtrate in the proximal tubules relies on the high-affinity folate receptor FRα through a process of transcytosis. In the diagram, the apical surface of polarized renal tubular epithelial cells is marked by an irregular contour.

Legend: FRα: folate receptor alpha; PCFT: proton-coupled folate transporter. (Source: Shulpekova Y, Nechaev V, Kardasheva S, et al. The concept of folic acid in health and disease. Molecules 2021;26(12):3731.) (Modified by Dr. Douglas Lanska. Creative Commons Attribution 4.0 [CC BY] license.)

Related Media