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Parathyroid adenoma (low magnification)

Low-magnification micrograph of the parathyroid adenoma (left side). Hematoxylin and eosin stain. Parathyroid adenomas as small, solitary, clearly demarcated nodules within the parathyroid gland. They consist of a single cell population forming a single mass, with a thin capsule, and no adipose tissue. The cells are usually arranged in a solid pattern, but it may variably have papillary or pseudoglandular (with gland-like spaces) patterns. In this case, normal parathyroid gland with prominent adipose tissue is seen on the right side of the image. (Courtesy of Wikimedia Commons. Creative Commons Attribution-Share Alike 3.0 Unported.)

Associated Disorders

  • Acute and chronic renal failure
  • Endocrine disorders
  • Familial hypocalciuric hypercalcemia
  • Granulomatous disorders
  • Infantile hypercalcemia (Williams syndrome)
  • Malignancy
  • Milk-alkali syndrome
  • Primary hyperparathyroidism