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Abdominal ultrasound showing a xanthine urinary stone in a patient with Lesch-Nyhan disease

The stone is echogenic with posterior acoustic shadowing. (Source: Shamir SB, Peng Q, Schoenfeld AH, Drzewiecki BA, Liszewski MC. CT, US and MRI of xanthine urinary stones: in-vitro and in-vivo analyses. BMC Urol 2020;20(1):157. Creative Commons Attribution 4.0 International License. http://creativecommons.org/licenses/by/4.0.)

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Associated Disorders

  • Choreoathetosis
  • Dystonia
  • Gout
  • Hyperuricemia
  • Intellectual disability
  • Renal stones