Neurofibromatosis 1 and intracranial neoplasms of childhood
Neurofibromatosis 1 is an autosomally dominated inherited genetic condition that predisposes those involved to the development of intracranial neoplasms. Visual pathway gliomas are the most common type of tumor encountered. Clinical manifestations of optic nerve involvement include unilateral or bilateral proptosis, decreased vision in 1 or both eyes, optic nerve pallor, and restricted extraocular movements.
Apr. 02, 2020