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Each lesion represents a separate nidus of infection that has disseminated from the initial site of inoculation. (Contributed by Dr. John Halperin.)
Neuropharmacology & Neurotherapeutics
Jun. 17, 2021
Childhood Degenerative & Metabolic Disorders
Mar. 10, 2021
Mar. 08, 2021
Nov. 13, 2020
Testing directly for LGI1 and contactin-associated protein 2 (CASPR2) antibodies should be undertaken in patients with clinical features suggestive of faciobrachial dystonic seizures, limbic encephalitis, Morvan syndrome, and neuromyotonia. LGI1-antibody seropositivity is most commonly associated with limbic encephalitis, with a high incidence of seizures and cognitive impairment. There is significant overlap in clinical manifestations with CASPR2 seropositivity, with neuromyotonia, pain, and sleep disturbance occurring across both clinical entities, albeit at different frequencies.
Jun. 08, 2020
Changes in sex-hormone levels during menarche, menstruation, pregnancy, and menopause may affect the prevalence and character of migraine and other types of headaches. Migraine occurring with menses may be characterized as menstrual migraine, menstrual-associated migraine, and non-migrainous perimenstrual headache. Migraine typically improves during pregnancy, mostly in the second and third trimesters. After menopause, when sex hormone levels stabilize, most women have improvement.
Oct. 23, 2016
Oct. 12, 2020
The basal ganglia are a set of subcortical gray matter structures historically associated with motor function but are also involved in critical cognitive and limbic functions. Emerging evidence suggests that the functional anatomy of the basal ganglia may not be fully accounted for in the standard “rate” model. Various movement disorders can be associated with patterned changes in oscillations and bursts in the substructures of the basal ganglia.
Nov. 21, 2020