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Mitochondrial abnormalities (photomicrograph)

Modified Gomori trichrome stain in Kearns-Sayre syndrome shows ragged-red fibers; the red stain in the subsarcolemmal regions of muscle fibers is due to accumulations of mitochondria. (Contributed by Dr. Michio Hirano.)

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Associated Disorders

  • DeToni-Fanconi-Debré syndrome
  • Diabetes mellitus
  • Pearson syndrome
  • Progressive external ophthalmoplegia