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Multiple sclerosis topographical model

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Multiple sclerosis--clinical events and age as a swimming pool, by Steve Krieger. Lesions lower the threshold for dysfunction when neurons are lost with age. (From: Laitman BM, Cook K, Fletcher M, Krieger SC. The topographical model of MS: empirical evaluation of the recapitulation hypothesis. Mult Scler J Exp Transl Clin 2018;4[4]:2055217318806527. Creative Commons Attribution 4.0 International [CC BY 4.0] license, creativecommons.org/licenses/by/4.0.)