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Internuclear ophthalmoplegia in multiple sclerosis

Internuclear ophthalmoplegia in multiple sclerosis

Often crucial in diagnosing multiple sclerosis and nearly pathognomonic, internuclear ophthalmoplegia consists of ipsilateral (to the direction of gaze) nystagmus and contralateral medial rectus weakness on lateral gaze. The traditional method to elicit this phenomenon, slowly following an examiner's finger, can miss medial rectus weakness. (Contributed by Dr. Anthony Reder.)

Related Media

Associated Disorders

  • Optic neuritis
  • Pars planitis (peripheral uveitis)
  • Seizure disorder
  • Transverse myelitis
  • Trigeminal neuralgia
  • Uveitis