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A coarse tremor appears in 1 or both arms, head, and trunk on any volitional movement; she is unable to approximate a target. (Courtesy of Dr. Sid Gilman.)
Neuropharmacology & Neurotherapeutics
Jul. 25, 2021
May. 01, 2020
Childhood Degenerative & Metabolic Disorders
Exome sequencing continues to enlarge the spectrum of single enzyme defects of peroxisomal beta-oxidation. In this article, the author highlights 4 patients
Nov. 01, 2018
Behavioral & Cognitive Disorders
Oct. 21, 2020
Neck pain, with or without radiating arm pain and associated root distribution paraesthesias, numbness, and motor deficit, is the classic presenting feature of cervical disc disease. The rupture of disc material through the annulus presents as an irritative mass against the centrally positioned spinal cord or laterally positioned root.
Jun. 23, 2021
Dimethyl fumarate was approved as a first-line oral treatment for relapsing forms of multiple sclerosis by the U.S. Food and Drug Administration in 2013. The most common adverse reactions for dimethyl fumarate as reported during clinical trials are flushing, mostly mild to moderate in nature, and gastrointestinal events. These events are most common at the start of therapy and usually decrease over time.
Nov. 02, 2020
Epilepsy & Seizures
Atonic seizures are epileptic attacks characterized by a sudden loss or diminution of muscle tone, which may be fragmentary, confined to a segment, or massive, leading to a slumping to the ground. They may have a generalized or focal origin, and may be brief (drop seizures) with patients able to stand up immediately if they fall; or prolonged (akinetic seizures), lasting from one to several minutes, where the patient falls to the ground and remains mute and motionless.
Aug. 01, 2019
In this article, the authors present recent data and discussion about the causes, syndromes, diagnosis, and management of hypermotor seizures.
Jan. 18, 2021