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Nerve biopsy in borderline leprosy

Nerve tissue has been replaced by an epithelioid granuloma. Epithelioid cells and lymphocytes surround Langerhans giant cell. (Hematoxylin and eosin stain, 625X) (Contributed by Ravindra Kumar Garg.)

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  • Antineutrophil cytoplasmic autoantibodies in serum
  • Arthritis
  • Asymptomatic hepatic infiltration
  • Blood: hemolytic anemia, megaloblastic anemia
  • Bone: osteomyelitis, osteoporosis, osteoperiostitis
  • Dapsone hypersensitivity syndrome
  • Dapsone-related motor neuropathy
  • Eyes: uveitis, iritis, iridocyclitis, corneal ulcers, blindness
  • Generalized lymphadenopathy
  • Gynecomastia
  • High serum antiphospholipid antibodies
  • Kidney: nephrotic syndrome, renal amyloidosis, glomerulonephritis
  • Larynx: fibrosis of vocal cords, laryngeal ulcer, hoarseness of voice
  • Neuropathic osteoarthropathy
  • Nose: rhinitis, crusting, epistaxis, anosmia, nasal collapse
  • Palatal perforation
  • Plantar ulcer
  • Testes: acute orchitis, testicular atrophy, azoospermia, hypogonadism
  • Thalidomide neuropathy
  • Ulnar neuritis
  • Vitiligo