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Non-contrast CT scans showing a bilateral, large subacute subdural hematoma. (Contributed by Dr. Ravindra Kumar Garg.)
Sep. 05, 2020
Neuro-Ophthalmology & Neuro-Otology
Leber hereditary optic neuropathy is a disease caused by various mutations in the mitochondrial genome and, as such, is inherited only via the maternal ovum as spermatozoa do not have mitochondria. It usually manifests as sequential binocular acute painless vision loss in sons of carrier mothers. The typical vision loss pattern is decreased visual acuity, with most patients seeing 20/200 or worse, a visual field defect involving the blind spot, and central fixation (cecocentral scotoma).
Dec. 19, 2020
Epilepsy & Seizures
Antiepileptic (or preferably antiseizure) drug treatment is the mainstay of the management of epilepsies and is generally recommended after 2 or more unprovoked seizures. The aim of antiepileptic drug treatment is to achieve seizure freedom without adverse drug reactions. Selection of antiepileptic drugs should be individualized based on the seizure type or epilepsy syndrome, potential adverse effects, and drug-to-drug interactions.
Jun. 09, 2018
Stroke & Vascular Disorders
Transient ischemic attacks, ischemic stroke, intellectual dysfunction, and hemorrhagic symptoms can occur with Moyamoya disease. It is an idiopathic non-atherosclerotic vasculopathy with characteristic angiographic abnormalities involving the terminal internal carotid artery and its branches.
Apr. 01, 2020
Genetic and acquired hypercoagulable states, such as factor V Leiden deficiency and antiphospholipid syndrome, are associated with cerebrovascular events, including cerebral venous thrombosis and ischemic stroke. The clinical manifestations of thrombophilic patients can be due to either venous thrombosis or (rarely) arterial thrombosis. The most common presentation of venous thrombosis is deep vein thrombosis of the lower extremity with or without pulmonary embolism.
Jul. 06, 2020
Fatal familial insomnia is a prion disease characterized by loss of sleep, oneiric stupors with dream enactment, autonomic activation, and somatomotor
Jan. 18, 2021
May. 24, 2021
Aug. 31, 2020