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Diagnostic and management strategy for patients with suspected thrombotic thrombocytopenic purpura

The pretest probability of thrombotic thrombocytopenic purpura should be determined based on clinical presentation and laboratory results. Note that all are conditional recommendations in the setting of low certainty of evidence. (Contributed by Dr. Fernando Testai. For detailed information, refer to: Zheng XL, Vesely SK, Cataland SR, et al. ISTH guidelines for the diagnosis of thrombotic thrombocytopenic purpura. J Thromb Haemost 2020;18(10):2486-95.)

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