Behavioral & Cognitive Disorders
Progressive subcortical gliosis
May. 22, 2023
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Psychotropic medications, designed to alter brain chemistry and treat various mental health disorders, have been found to impact the default mode network both in individuals with neurologic disorders and in healthy volunteers. The default mode network, which is active during rest and involved in self-referential thought and mind-wandering, is altered in many psychiatric conditions. Understanding how psychotropic medications affect the default mode network can provide insights into their mechanisms of action and therapeutic effects.
It is important to note that the impact of psychotropic medications on the default mode network can vary widely depending on the specific drug, the dosage, the duration of treatment, and individual differences in brain chemistry and psychiatric conditions. Moreover, the relationship between default mode network changes and clinical outcomes is complex and not fully understood. As research in this area continues to evolve, it will provide a more nuanced understanding of how these medications exert their effects on the brain and how they can be optimally used in treatment.
Related MedLink Neurology content:
Neuroscience: Origins and relevance of the default mode network
Neuroscience: Cataloguing default mode network disruption in neurologic disorders
MedLink acknowledges the use of GPT-4 in drafting this blog entry.