Mar. 05, 2021
Acromegaly due to ectopic secretion of GHRH by a pancreatic tumor that has metastasized to the liver (left). This has caused pituitary hyperplasia, which is visible on a coronal MRI of the pituitary (right), as well as hyperstimulation of normal somatotroph cells, leading to growth hormone hypersecretion and acromegaly. Source: Chanson and Salenave 2008. Creative Commons Attribution License 2.0 Generic (CC BY 2.0).