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Acromegaly: appearance soon after the onset of symptoms

Patient, 26 years of age. Compared with the photograph from 1 year earlier, there is a marked change in appearance: the lips are thicker, the nose and ears are larger, and the hair is coarser. (Gibson case “MC” and Geddes case “EAS 07.”) (Source: Gibson GA. Acromegaly. Edinburgh Med J 1899;6[6]:505-21. Public domain.)