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Oct. 21, 2020
Anti-GD1b IgG or IgM antibodies are associated with acute or chronic ataxic neuropathy syndromes respectively, which may arise as acute postinfectious syndromes or as chronic paraproteinemia-associated syndromes. Sensory ataxic variants of Guillain Barré syndrome are often associated with anti-GD1b IgG antibodies.
Feb. 18, 2019
Headache & Pain
Neuropathic pain is defined as pain initiated or caused by a primary lesion or dysfunction in the nervous system. Central neuropathic pain is associated with CNS lesions, eg, stroke and spinal cord injury. There are several central pain syndromes with different clinical presentations and underlying neurologic abnormalities, eg, central poststroke pain, central pain in Parkinson disease, etc., and prognosis varies according to the primary pathology.
Feb. 26, 2021
Jun. 01, 2020
Behavioral & Cognitive Disorders
Fragile X syndrome is the most common inherited cause of cognitive impairment in males. The most common problems are cognitive impairment and behavioral disturbances, with 4% to 8% of cognitive impairment or developmental delay caused by fragile X mutation. The clinical severity is directly related to the number of repeats in the FMR1 gene.
Jan. 06, 2021
Automatic-voluntary dissociation refers to the differential completion of an action depending on the patient’s attention to the task, whether performed attentively (“voluntarily”) or inattentively (“automatically”), and is not specific to a form of neuropathology or lesion localization. Dissociation can occur in either direction, with some illnesses resulting in preserved “automatic” acting but impaired “voluntary” acting, and others having the opposite pattern.
Aug. 15, 2021
Stroke & Vascular Disorders
Atrial fibrillation is the most common sustained cardiac arrhythmia and the most common cause of cardioembolism. It confers a 3- to 5-fold increase in stroke risk and accounts for 15% to 30% of all ischemic strokes. Patients present with severe deficits and clinical evidence of cortical or cerebellar dysfunction. The most current guidelines for the prevention of stroke recommend the correction of modifiable vascular risk factors.
Jan. 18, 2021
Oct. 12, 2020