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Aug. 17, 2019
Stroke & Vascular Disorders
Lacunar infarcts are small infarcts in the deep cerebral white matter, basal ganglia, or pons, caused by occlusion of a single penetrating branch of a large cerebral artery.
Nov. 17, 2017
General Child Neurology
Literature focused on the physiologic mechanisms of cerebral edema in the pediatric population is limited and often extrapolated from the adult population;
Mar. 11, 2019
Childhood Degenerative & Metabolic Disorders
GM2 gangliosidoses are caused by beta-hexosaminidase deficiency. There are 2 major phenotypes: Tay-Sachs disease, caused by beta-hexosaminidase A deficiency, and Sandhoff disease, caused by beta-hexosaminidase A and B deficiency. Carrier detection in risk populations is successful in prevention.
May. 25, 2019
Neuropharmacology & Neurotherapeutics
Serotonin syndrome is due to the toxic effect of excess of serotonin activity. It may result from an overdose of serotonergic drugs as well as drug interactions, the most common of which occurs between serotonergic agents and MAO inhibitors. Clinical manifestations inlude mental status change, agitation, myoclonus, hyperreflexia, diaphoresis, shivering, tremor, diarrhea, incoordination, and fever.
Sep. 13, 2020
Mar. 20, 2021
Involvement of the peripheral nervous system is the most common clinically manifest neurologic complication of rheumatoid arthritis, but cervical spine abnormalities can also occur. Complications can affect the central nervous system, peripheral nervous system, muscles, and neuromuscular junction.
Jan. 11, 2021
Jun. 17, 2021