Tuberous sclerosis complex
Seizures, cortical dysplasia, tumors, intellectual disability, autism, ADHD, and sleep disorders are all CNS manifestations of tuberous sclerosis complex, occuring in about 90% of patients. Cortical dysplasia is also common, manifesting as cortical tubers and lines of migration. It is an autosomal-dominant genetic disorder.
Aug. 24, 2021