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Neurotoxin sodium channel binding sites

The diagram illustrates the membrane topology of a voltage-gated sodium channel protein. Binding sites for different neurotoxins are indicated by color. Abbreviations: TTX, tetrodotoxin; STX, saxitoxin. Image by Kathleen Cusick and Gary Sayler on April 11, 2013. (See: Cusick KD, Sayler GS. An overview on the marine neurotoxin, saxitoxin: genetics, molecular targets, methods of detection and ecological functions. Mar Drugs 2013;11[4]:991-1018. Creative Commons Attribution-Share Alike 3.0 Unported License,