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French physician and physiologist Denis Jourdanet (1815-1892) in 1866

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Photogravure, after a photograph. Jourdanet spent many years in Mexico studying the effects of high altitude. (West JB, Richalet JP. Denis Jourdanet [1815-1892] and the early recognition of the role of hypoxia at high altitude. Am J Physiol Lung Cell Mol Physiol 2013;305[5]:L333-40). (Source: Courtesy of the Wellcome Collection, London, England. Creative Commons Attribution 4.0 International [CC BY 4.0] License, https://creativecommons.org/licenses/by/4.0. Figure restored and edited by Dr. Douglas J Lanska.)