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Intramedullary metastatic tumor with pencil-shaped necrosis of the spinal cord (photomicrograph)

(Left) Two symmetrically placed, intramedullary metastatic tumors have destroyed the first sacral segment of the spinal cord. (Hematoxylin-eosin; x7.8) (Center) Rostral to the tumors, the entire fifth lumbar segment has undergone coagulation necrosis, and the central portion has begun to liquefy. (Luxol fast blue; x8) (Right) Still more rostral, in the sixth thoracic segment, only the ventral portion of the dorsal columns is necrotic. (Hematoxylin-eosin; x7.2) (Contributed by Dr. Marc D Winkelman.)

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Associated Disorders

  • Breast cancer
  • Cerebral metastasis
  • Leptomeningeal metastasis
  • Lung cancer
  • Lung metastases
  • Melanoma
  • Small cell carcinoma of the lung