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MRI shows large sellar mass extending into sphenoid sinus. (Contributed by Dr. Sudhir Kothari.)
Oct. 21, 2020
Cervical dystonia is the most common focal dystonia, consisting of involuntary head and neck movements, which result in abnormal postures, tremor, and associated pain. The most prominent feature is usually sustained rotational deviation of the head to one side. Neck pain is a common feature of cervical dystonia.
Jan. 24, 2021
Facioscapulohumeral muscular dystrophy can manifest with protruding scapulae, difficulty raising the arms (often asymmetrically) and lifting objects, and progresses to include truncal muscles as well as lower extremity muscles. About 20% of patients are wheelchair dependent after age 50. Inheritance is autosomal dominant in most with a high incidence of sporadic cases due to de novo mutations.
Dec. 28, 2020
Neurologic complications from systemic anticancer therapies impact quality of life and remain an important source of dose-limiting toxicity. These complications may result from the direct toxic effects of the drug on the nervous system or indirectly from metabolic derangements, inflammatory responses, or cerebrovascular disorders induced by the drugs. The neurotoxicities of chemotherapy are widely known, but targeted agents and immunotherapies are also associated with neurologic complications.
Dec. 19, 2020
Epilepsy & Seizures
Focal clonic seizures are a type of neocortical seizure emanating from the contralateral primary motor cortex. They are repetitive, brief and rhythmic, unilateral, and rapidly alternating contractions and relaxations of localized groups of muscles. They may affect the thumb only, the thumb and ipsilateral side of the lips, the hand, the whole arm, or any other contralateral to the focus body part.
Mar. 21, 2020
Jul. 01, 2020
Stiff-person syndrome is a rare disorder that causes continuous muscle contractions with spasms, abnormal postures, and progressive disability. It is often associated with other autoimmune signs and symptoms as well as nonspecific and organ-specific autoantibodies. The symptoms of stiff-person syndrome likely relate to cortical and spinal cord hyperexcitability secondary to reduction of GABA.
Sep. 26, 2021
Oct. 06, 2020