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Contrast enhanced, T1-weighted, sagittal image, showing an enhancing, discrete, intradural tumor lateral to the deviated spinal cord. (Contributed by Dr. Sherman Stein.)
Neuropharmacology & Neurotherapeutics
Mar. 10, 2021
Childhood Degenerative & Metabolic Disorders
Mar. 07, 2020
Epilepsy & Seizures
Oct. 14, 2009
Stroke & Vascular Disorders
Neurologic complications continue to be recognized as important factors in postoperative morbidity from cardiovascular procedures. The occurrence of strokes and seizures that complicate cardiac surgical procedures can be as high as 7% and 1%, respectively. Neurologic injury, such as stroke or seizure, is a strong independent predictor of neurologic morbidity and mortality as well as quality of life.
Feb. 12, 2019
Cerebellar hypoplasia is a feature of several neurodevelopmental disorders in which the cerebellum is small in size, but normal in shape. Disorganized development of the cerebellum causes cerebellar dysplasia in which the shape and “texture” of the cerebellum appear abnormal due to the presence of abnormal folia pattern or gray matter nodular heterotopia. Macrocerebellum is a rare malformation that may occur as an isolated finding or as part of a few syndromes.
Sep. 08, 2021
Dysphagia usually manifests as a sensation of "stickiness" or difficulty in swallowing food. In upper oropharyngeal dysphagia, there is difficulty in initiating the act of swallowing, but once initiated, swallowing is completed normally. In esophageal dysphagia, the swallowed food may eventually navigate the esophagus or may be regurgitated or vomited if the obstruction is severe. Dysphagia is frequent in neurodegenerative disorders, such as Parkinson disease.
Nov. 07, 2020
Behavioral & Cognitive Disorders
Parkinson disease (PD) dementia is clinically distinct from other forms of dementia. Core features include a diagnosis of PD and a dementia syndrome leading to impairment in more than one cognitive domain, deficits impairing daily life, and a decline from premorbid functioning. Attention (particularly fluctuations), visuospatial construction, and executive function are more impaired in PD dementia compared with Alzheimer disease. In general, short-term memory and language are less impaired compared to Alzheimer disease.
Oct. 20, 2020
Patients with polymyositis commonly present with a myopathy characterized by proximal and often symmetric muscle weakness manifested as difficulty performing tasks requiring the use of proximal muscles. Polymyositis has no unique clinical features, and its diagnosis is one of exclusion. Most patients described as having polymyositis actually have another disease—either inclusion body myositis, necrotizing autoimmune myositis, or antisynthetase syndrome.
May. 03, 2021