General Neurology
Intraoperative neurophysiological monitoring
Jun. 17, 2024
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Toll Free (U.S. + Canada): 800-452-2400
US Number: +1-619-640-4660
Support: service@medlink.com
Editor: editor@medlink.com
ISSN: 2831-9125
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Dystroglycan is a transmembrane protein connecting the cell to extracellular ligands, such as laminin. Alpha- and beta-dystroglycan (DG) are shown in purple. The site of action of each glycosyltransferase mutated in dystroglycanopathies is indicated at the respective bonds on the functional glycan. Abbreviations: Man= mannose, GlcNac=N-acetylglucosamine, GalNac=N-acetylgalactosamine, Gal=galactose, RboP=ribitol phosphate, Xyl=xylose, GlcA=glucuronic acid. (The figure was partially created with BioRender. Contributed by Dr. Maria Chiara Manzini.)