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BrainWaves #9 Teaching through clinical cases: Painless ophthalmoparesis

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021.

Originally released: July 18, 2017

Our 9th episode features an evolving case discussion about a patient with eye movement difficulties. Dr. Ali Hamedani navigates us through the orbit, brainstem, and midbrain as we discern the structural and physiological problems that can impede extra-ocular movements. BrainWaves podcasts and online content are intended for medical education only and should not be used to guide medical decision-making in routine clinical practice. Any cases discussed in this episode are fictional and do not contain any patient health-identifying information. This episode was vetted and approved by Grant Liu.


Brent GA. Clinical practice. Graves' disease. N Engl J Med 2008;358(24):2594-605. PMID 18550875

Chiba A, Kusunoki S, Obata H, Machinami R, Kanazawa I. Serum anti-GQ1b IgG antibody is associated with ophthalmoplegia in Miller Fisher syndrome and Guillain-Barré syndrome: clinical and immunohistochemical studies. Neurology 1993;43(10):1911-7. PMID 8413947

Cornblath WT. Diplopia due to ocular motor cranial neuropathies. Continuum (Minneap Minn). 2014 Aug;20(4 Neuro-ophthalmology):966-80. PMID 25099103

Dallow RL, Pratt SG. Approach to orbital disorders and frequency of disease occurrence. In: Albert DM, Jakobiec FA, editors. The Principles and Practices of Ophthalmology: Clinical Practice. v3. WB Saunders Co.: Philadelphia, 1994.

Liu GT, Volpe NJ, Galetta SL. Neuro-Ophthalmology: Diagnosis and Management. 2nd ed. Elsevier, 2010.

Sanders DB, Guptill JT. Myasthenia gravis and Lambert-Eaton myasthenic syndrome. Continuum (Minneap Minn) 2014;20(5 Peripheral Nervous System Disorders):1413-25. PMID 25299290

We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode’s original release date.

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