Behavioral & Cognitive Disorders
Normal pressure hydrocephalus
Mar. 06, 2023
Nearly 3,000 illustrations, including video clips of neurologic disorders.
Every article is reviewed by our esteemed Editorial Board for accuracy and currency.
Full spectrum of neurology in 1,200 comprehensive articles.
Listen to MedLink on the go with Audio versions of each article.
From left to right: The lysosomal storage disorders, the gene defect, accumulating lysosomal GSL substrates, and the deacylated lyso-GSL species.
Abbreviations: ASA, Arylsulfatase A; GALC, β-galactosylceramidase; GalCer, galactosylceramide; GBA, acid β-glucosidase; GLA, α-galactosidase A; GLB1, β-galactosidase; GB3, globotriaosylceramide; GlcCer, glucosylceramide; GM1, ganglioside GM1; GM2, ganglioside GM2; HEX, β-hexosaminidase; lyso-GSL, lyso-glycosphingolipid; SO, sphingoid.
(Source: van Eijk M, Ferraz MJ, Boot RG, Aerts JM. Lyso-glycosphingolipids: presence and consequences. Essays Biochem 2020;64:565-78. Creative Commons Attribution License 4.0 [CC BY], https://creativecommons.org/licenses/by/4.0.)