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Response of high-altitude periodic breathing to administration of oxygen during the 1911 Anglo-American Expedition to Pikes Peak

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July 16, 1911. Subject: John Scott Haldane. Natural periodic breathing abolished by administration of oxygen. Reappearance of periodic breathing on withdrawing the oxygen. Subject breathing through valves throughout. (Source: Douglas CG, Haldane JS, Henderson Y, Schneider EC. Physiological observations made on Pike's Peak, Colorado, with special reference to adaptation to low barometric pressures. Philosophical Transactions of the Royal Society, Series A 1913;203:185-318.)