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Time course of SpO2 (blue) and pulse (green) in a patient with HAPE at 4380 m (14,370 ft)

The black lines indicate the beginning and end of Auto-PEEP breathing. (Source: Tannheimer M, Lechner R. Initial treatment of high-altitude pulmonary edema: comparison of oxygen and auto-PEEP. Int J Environ Res Public Health 2022;19[23]:16185. Creative Commons Attribution [CC BY 4.0] license,