General Child Neurology
Central hypotonia in infancy and childhood
Hypotonia is reduced tension or resistance of passive range of motion and can occur with varying degrees of weakness. Central hypotonia is more likely to be noted axially with normal strength and hyperactive to normal deep tendon reflexes. Other clinical signs will vary by specific etiology. Examples include dysmorphic features associated with specific genetic disorders or multiorgan involvement in many metabolic disorders.
Aug. 24, 2020