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Catabolic route of glycosphingolipid generation in Gaucher disease

(Source: Revel-Vilk S, Fuller M, Zimran A. Value of glucosylsphingosine (Lyso-Gb1) as a biomarker in Gaucher disease: a systematic literature review. Int J Mol Sci 2020;21[19]:7159. Creative Commons Attribution 4.0 International [CC BY 4.0] license, See also: Aerts JM, Kuo CL, Lelieveld LT, et al. Glycosphingolipids and lysosomal storage disorders as illustrated by Gaucher disease. Curr Opin Chem Biol 2019;53:204-15. Figure modified by Dr. Douglas J Lanska.)