10393 San Diego Mission Rd, Suite 120
San Diego, CA 92108-2134
Toll Free (U.S. + Canada): 800-452-2400
US Number: +1-619-640-4660
Glucocerebrosidase accumulation in the spleen produces fibrotic scars and nodules. (Contributed by Dr. John Barranger.)
May. 10, 2021
Neuropharmacology & Neurotherapeutics
Sep. 12, 2021
Hormonal imbalance changes associated with the menstrual cycle, pregnancy, menopause, and use of oral contraceptives can influence many neurologic conditions. Estrogens exert neuroprotective effects against development or progression of brain diseases. Fluctuating sex hormone levels also influence the expression of certain neuropsychiatric states and neuroendocrine disorders.
May. 15, 2021
Neuro-Ophthalmology & Neuro-Otology
Postural orthostatic tachycardia syndrome (POTS) is an often-disabling syndrome of symptomatic orthostatic tachycardia in the absence of orthostatic hypotension. POTS has been associated with a wide variety of conditions, including diabetes, some autoimmune disorders, infections, trauma, surgery, stress, mastocytosis, and the hypermobility type of Ehlers-Danlos syndrome. Palpitations, dizziness, and other symptoms of POTS occur mainly when standing upright and are typically relieved by sitting or lying flat.
Dec. 12, 2020
Epilepsy & Seizures
In this article, the authors present recent data and discussion about the causes, syndromes, diagnosis, and management of hypermotor seizures.
Jan. 18, 2021
Topiramate is a monosaccharide derivative with a sulfamate functionality. It is used as an add-on therapy to other antiepileptic drugs with the aim of controlling seizures as completely as possible. Those who tolerate topiramate have a good chance of seizure control. It is indicated for use in partial-onset seizures in adults and prophylaxis of migraine.
Jul. 11, 2021
Jun. 23, 2021
Stroke & Vascular Disorders
Cardioembolic strokes are more severe clinically than other forms of stroke, with atrial fibrillation as the leading source. Clinical manifestations of cerebral embolism depend on the arterial territory affected and the eloquence of the ischemic tissue. Embolic material usually originates from the heart or great vessels such as the aortic arch or carotid bifurcation.
Mar. 06, 2018