Sign Up for a Free Account

This is an image preview.
Start a Free Account
to view the full image.

Sign Up for a Free Account For information on discounts, see Plans & Pricing

  • Nearly 3,000 illustrations, including video clips of neurologic disorders.

  • Every article is reviewed by our esteemed Editorial Board for accuracy and currency.

  • Full spectrum of neurology in 1,200 comprehensive articles.

  • Listen to MedLink on the go with Audio versions of each article.

Cutaneous hyperpigmentation in man with megaloblastic anemia

Photos of 52-year-old vegetarian Indian man with diffuse brownish-black pigmentation over dorsal aspect of feet (C1) and dusky, brownish-black discoloration of palms with accentuation of palmar creases (C2). Laboratory studies showed pancytopenia, macrocytosis (MCV 115fL), and florid megaloblastic anemia proven on bone marrow examination (B12 and folate assay not done). (Source: Padhi S, Sarangi R, Ramdas A, et al. Cutaneous hyperpigmentation in megaloblastic anemia: a five year retrospective review. Mediterr J Hematol Infect Dis 2016;8[1]:e2016021. Creative Commons Attribution 2.0 License.)

Related Media

Associated Disorders

  • Alcohol-tobacco amblyopia
  • Cerebral vascular disease
  • Dementia
  • Depression
  • Developmental delay
  • Folate deficiency
  • Gastric resection
  • Glossitis
  • Imerslund-Grasbeck syndrome
  • Malabsorption
  • Megaloblastic anemia
  • Myelopathy
  • Optic neuropathy
  • Pernicious anemia
  • Polyneuropathy
  • Regional enteritis
  • Subacute combined degeneration of the spinal cord