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Tissue block from sella turcica in holoprosencephalic cyclopic fetus

Left schematic drawing and right histological sagittal paraffin section of a tissue block from the sella turcica region in a human holoprosencephalic cyclopic fetus, gestational age 16 weeks. Anterior direction is left. Note the craniopharyngeal canal penetrating the cranial base below the pituitary gland. Adenohypophyseal tissue is located in the sella turcica, in the canal and in the pharyngeal mucosa. Neurohypophyseal tissue is seen in the sella. (Toluidine blue)

Associated Disorders

  • Anencephaly
  • CHARGE syndrome
  • Cleft lip and palate
  • Duplication of pituitary stalk
  • Ectopic neurohypophysis
  • Empty sella syndrome
  • Holoprosencephaly
  • Hypertelorism
  • Midfacial anomalies
  • Myelomeningocele
  • Pallister-Hall syndrome
  • Pituitary agenesis
  • Pituitary aplasia
  • Pituitary dysplasia
  • Pituitary ectopia
  • Pituitary hypoplasia
  • Rachischisis
  • Rathke cleft cyst
  • Rieger syndrome
  • Rubinstein-Taybi syndrome
  • Septo-optic dysplasia
  • Solitary maxillary central incisor
  • Spina bifida