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(Contributed by Dr. R L Wollmann, University of Chicago.)
Dec. 04, 2020
Sep. 22, 2020
Patients who have neuromuscular disorders are at high risk for development of sleep-related respiratory disorders and respiratory failure. Patients with weakness or paresis of the diaphragm have the highest risk of respiratory compromise during REM sleep. Fortunately, most patients will respond favorably to application of positive airway pressure, but the diagnosis of respiratory compromise during sleep needs to be ascertained.
May. 15, 2021
Neuropharmacology & Neurotherapeutics
Sep. 04, 2021
Carbon monoxide poisoning can produce several nonspecific symptoms and can mimic several diseases. Most of the effects are due to hypoxia. Neurologic sequelae are significant and may be delayed in onset. Hyperbaric oxygen plays an important role in the management of carbon monoxide poisoning.
Mar. 28, 2021
Behavioral & Cognitive Disorders
Foix-Chavany-Marie syndrome is a rare cortical form of supranuclear (pseudobulbar) palsy caused by bilateral anterior opercular lesions; in this syndrome there is an “automatic-voluntary dissociation” of motor function of lower cranial nerves. Manifestations include volitional paralysis of masticatory, facial, pharyngeal, and lingual muscles innervated by cranial nerves V, VII, IX, X, and XII, with preserved autonomic and emotional innervation of these muscles. There are 5 predominant clinical groups of Foix-Chavany-Marie syndrome.
Oct. 21, 2020
Headache & Pain
Indomethacin elicits a prompt and complete response in certain primary headache disorders. Trigeminal autonomic cephalalgias and Valsalva-induced headaches are among the most responsive. It inhibits both cyclooxygenase 1 and cyclooxygenase 2 and leukocyte activity, decreases cerebral blood flow and CSF pressure, and has antipyretic, anti-inflammatory, and analgesic properties.
Oct. 02, 2019
Defecation and micturition syncopes are forms of the so-called situational syncopes, which occur immediately after precipitating situations, such as urination and defecation. There may be associated brief jerking or rhythmic movements, but there is no associated incontinence, tongue biting, or postictal state. Recovery usually occurs within seconds without vasomotor or other sequelae. Patients are amnestic for the period of lost consciousness.