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This T2-weighted MRI identifies white matter changes over the more superior right corona radiate in the brain of an elderly patient with diabetes and gait abnormality. (Contributed by Dr. Cory Toth.)
Aug. 17, 2019
Stroke & Vascular Disorders
Clinical studies have determined associations between the occurrence of white matter abnormalities in the brain and cognitive decline and gait impairment, as well as increased relative risk for cerebrovascular disease. Besides abnormalities in cognition, physical examination signs that relate most commonly to the presence of white matter abnormalities include an extensor plantar reflex and the presence of primitive reflexes.
Jul. 21, 2016
Intracerebral hemorrhage is characterized by sudden onset of focal neurologic deficit progressing over hours along with headache, nausea, vomiting, altered consciousness, and hypertension. It most commonly results from hypertensive damage to blood vessels, and is a common cause of stroke.
Mar. 18, 2021
Headache & Pain
New daily persistent headache is a daily headache syndrome that starts acutely and can only be diagnosed after 3 months have elapsed and other secondary and primary headache diagnoses have been excluded. There are 2 subtypes based on the clinical features of headache–migrainous or nonmigrainous. The prognosis varies; however, the treatment approach is largely extrapolated from the management of other forms of chronic daily headache.
May. 10, 2017
General Child Neurology
Pediatric presentation of Guillain-Barré syndrome differs from that of adults with predominant symptoms of gait ataxia or pain, and a higher incidence of cranial nerve abnormalities. Weakness of the respiratory muscles can be the most serious complication. Clinical manifestations in children are often anteceded within 2 to 4 weeks by recent illness or immunization.
Nov. 23, 2020
Sleep bruxism is a repetitive jaw-muscle activity characterized by clenching or grinding of the teeth or by bracing or thrusting of the mandible. A sequential change from autonomic and brain cortical activities precedes sleep bruxism, and growing evidence indicates that emotions, psychological stress and predisposition to anxiety can play a role in onset.
Oct. 27, 2020
Amyloidosis refers to the extracellular deposition of fibrils composed of low weight chain of a variety of normal serum proteins. The autosomal dominant hereditary transthyretin amyloidosis (hATTR) and the acquired light chain (AL)-amyloidosis, the result of a plasma cell dyscrasia, are the 2 most common types of amyloidosis associated with peripheral neuropathy. In both, the main presentation is a painful, length-dependent small fiber neuropathy starting in the feet, with numbness, burning and allodynia, which can be particularly worse at night.
Feb. 12, 2020
Jan. 05, 2021