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White matter lesions in multiple sclerosis (T1-weighted MRI)

This is a T1-weighted MRI of the brain with gadolinium provision of a young female patient with clinically definite multiple sclerosis. Several lesions demonstrate gadolinium enhancement, most typical for active demyelinating disease. This finding would not be expected to occur with white matter abnormalities not due to demyelinating disease. (Contributed by Dr. Cory Toth.)

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  • AIDS-related dementia
  • Adrenoleukodystrophy
  • Alzheimer disease
  • Kearns-Sayre syndrome
  • Krabbe disease (globoid cell leukodystrophy)
  • Leigh disease (subacute necrotizing encephalomyelopathy)
  • Susac syndrome
  • cytomegalovirus infection
  • dementia
  • diabetes
  • diabetes mellitus
  • hypertension
  • lacunar stroke
  • metachromatic leukodystrophy
  • migraine
  • mitochondrial encephalopathy with lactic acidosis and stroke-like episodes (MELAS)
  • myotonic dystrophy
  • pediatric dysmyelinating disorders
  • pyridoxine deficiency
  • stroke
  • vascular dementia