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Osmotic demyelination syndrome in alcoholic patient with rest tremor

T1 post-contrast MRI showing demyelination (A) of the pons, sparing the corticospinal tracts (asterisks) and peripheral pontine fibers (arrows). This pattern has been likened to a trident (B) or pig snout (not shown). (Source: Ahmed M, Moffett P. Osmotic demyelination syndrome in a patient with tremors. Cureus 2022;14[10]:e30076. Creative Commons Attribution license [CC BY],

Associated Disorders

  • Alcoholism
  • Extrapontine myelinolysis
  • Hyperosmolar hyperglycemic state
  • Hypokalemia
  • Malnutrition
  • Osmotic myelinolysis