Sign Up for a Free Account

This is an image preview.
Start a Free Account
to view the full image.

  • Nearly 3,000 illustrations, including video clips of neurologic disorders.

  • Every article is reviewed by our esteemed Editorial Board for accuracy and currency.

  • Full spectrum of neurology in 1,200 comprehensive articles.

  • Listen to MedLink on the go with Audio versions of each article.

Osmotic demyelination syndrome (macroscopic section of brain) (1)

Macrosection of pons from a patient with central pontine myelinolysis showing central area of demyelination. Preservation of myelin in pontine tegmentum (top portion) distinguishes this lesion from multiple sclerosis. Preservation of the most ventral (bottom) myelin and preservation of neurons distinguishes this lesion from infarction. (Contributed by Dr. Jack Riggs.)

Associated Disorders

  • Alcoholism
  • Extrapontine myelinolysis
  • Hyperosmolar hyperglycemic state
  • Hypokalemia
  • Malnutrition
  • Osmotic myelinolysis