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Severe neonatal myotonic dystrophy (quadriceps femoris muscle biopsy) (3)

Transverse frozen section stained with NADH-TR shows strong mitochondrial oxidative enzymatic activity in the centers of many myofibers, corresponding to the clear spaces seen in some myofibers with hematoxylin and eosin stain. X250. (Reproduced with permission from: Sarnat HB, O’Connor T, Byrne PA. Clinical effects of myotonic dystrophy on pregnancy and the neonate. Arch Neurol 1976;33:459-65. Copyrighted 1976, American Medical Assoc.)

Related Media

Associated Disorders

  • Steinert disease, neonatal form
  • congenital myopathies
  • myotonic disorders