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Glucose transporters in the brain: Glut1 and Glut3

Representation of the main glucose transporters in the brain--GLUT1 and GLUT3--both belonging to the group of facilitated “passive” transporters (encoded by members of the SLC2 gene family). Legend: Transport across cell membranes (arrows); localization and known defects of Glut1 (green rectangular symbols); Glu, glucose; CSF, cerebrospinal fluid. (Source: Vulturar R, Chis A, Pintilie S, et al. One molecule for mental nourishment and more: glucose transporter type 1-biology and deficiency syndrome. Biomedicines 2022;10[6]:1249. Creative Commons Attribution License [CC BY], Figure edited by Dr. Douglas J Lanska.)